TB-500 is a synthetic form of Thymosin Beta 4 that occurs naturally in animal cells. The peptide is one of the members of 16 related molecules’ ubiquitous family. TB-500 is utilized by the body to improve differentiated endothelial cells functions and associated physiological roles. The molecule acts by regulating the cellular skeleton protein called actin. The latter represents about 10% of the total cellular proteins, vital for cellular and genetic architecture. The synthetic peptide is widely studied for its anti-inflammatory and wound healing properties. Research evidences suggest that TB-500 might be useful for skin and muscle building. Due to low molecular weight, the synthetic peptide is able to migrate to distant organ sites. TB-500 aids keratinocyte and endothelial migration. Speculated to be an up-regulated gene, TB-500 administration accelerates angiogenesis and hematopoiesis by 4-6 times than normal rate. The molecular weight of TB-500 is 4963.44 and molecular formula is C212H350N56O78S.

According to studies, the hormone promotes muscle building, wound healing, and speeds up muscle recovery when it is administered subcutaneously. One of the most important aspects of the TB-500, the central small amino acid long actin-binding domain has cell production and wound healing properties. This is more accentuated by the migration of the keratinocyte and endothelial cells; moreover, it increases the production of extracellular matrix-degrading enzymes. One key mechanism of TB-500 is the regulation of cell building proteins; actin is an essential component in wound healing and production of new cells. TB 500 is vital in cell differentiation, proliferation and maturity, studies also reveal that the functioning o the cells depend on the level of the hormone. Thymosin beta 4 plays a crucial role in the deposition  of collagen thereby reducing inflammation.

TB-500 Chemical Profile

CAS: 77591-33-4

Formula: C212H350N56O78S

Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

Molecular weight: 4963.44

Peptide purity: > 99.0%