Description

Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10), specifically engineered for neuroprotective and cognitive enhancement applications. Developed through systematic peptide modification research in Russia, Semax (Met-Glu-His-Phe-Pro-Gly-Pro) represents a breakthrough in rational peptide design, optimized to enhance cognitive function while providing robust protection against neurological injury without the hormonal side effects of native ACTH.

This peptide has gained considerable attention in neurology and cognitive medicine due to its demonstrated multifaceted benefits in stroke recovery, traumatic brain injury rehabilitation, and cognitive performance optimization through comprehensive modulation of neurotransmitter systems, gene expression regulation, and neuroprotective pathways. Semax exhibits excellent CNS penetration via intranasal administration and maintains bioactivity across various physiological conditions, making it unique among neuroprotective peptides.